IMMUNOBIOLOGY Reciprocal regulation of human natural killer cells and macrophages associated with distinct immune synapses
نویسندگان
چکیده
1Division of Cell and Molecular Biology, Imperial College London, South Kensington Campus, United Kingdom; 2Department of Pathology, Cambridge Institute for Medical Research, Addenbrookes Hospital, United Kingdom; 3Sir William Dunn School of Pathology, University of Oxford, United Kingdom; 4Centre d’Immunologie de Marseille-Luminy, Centre National de la Recherche Scientifique (CNRS)–Institut National de la Santé et de la Recherche Médicale (INSERM)–Université de la Méditerranée, Campus de Luminy, Marseille, France; 5Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy
منابع مشابه
Reciprocal regulation of human natural killer cells and macrophages associated with distinct immune synapses.
Natural killer (NK) cells directly lyse tumor or viral-infected cells but also an important role for NK cell cytotoxicity in regulating the extent of immune responses is emerging. Here, we show that autologous human macrophages activated NK cell proliferation and cytokine secretion, increased expression of activating receptors, and primed NK cell cytotoxicity against susceptible target cells. L...
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تاریخ انتشار 2007